Complex regional pain syndrome (crps) is the most painful condition known to the medical community. It’s a disease with no known cause, no diagnostic test, no proven treatment course to follow, and no cure.
Due to this rather gloom disease prognosis, I have kept my eye on current clinical trials for a better treatment solution or even a CURE from the research and medical community. Clinicaltrials.gov is a database, provided by the US National Library of Medicine, of current research studies in the US and many other countries.
This database allows you to search by disease or condition, drug name, country, or even investigator name. For each study there are links to better aid your research of the study to help you make a more informed decision prior to applying to participate.
Through searching for crps studies, My Great-Aunt Sue came across Grüenthal’s neridronic acid phase 3 clinical trial. After I started researching the drug, pharmaceutical company, and press releases regarding the trial’s process, I crossed my fingers and applied to be a participant. The next day I was accepted….then the study closed.
I spent the next 4 months emailing and calling study sites to see when the trial would open again. Thankfully I didn’t annoy the research coordinators too much and was accepted as a participant.
More on the CRPS neridronic acid clinical trial:
Neridronic acid is a biphosphate and has been used in Italy to successfully put crps in remission (up to 1 year at this point of patient follow-ups). In patients where complete remission was not achieved there was still significant pain and crps symptom relief starting 20 days post-treatment and even more relief at 40 days post. I found this extremely encouraging! When you live with a disease where you don’t know if tomorrow you will be able to walk or not and are tied to the hospital every week for treatment, any sort of relief sounds amazing!
The drug seems too good to be true so naturally I anticipated it would come with many risks and side effects. From what is known about neridronic acid that is not the case. Noted side effects are flu-like symptoms, bone-aches, decreased calcium and vitamin d blood levels.
More on my experience with the clinical trial to come.
*I am not a medical doctor, this is not medical advice. Consult a medical professional for all medical decisions.